|
KMID : 0356919950280020251
|
|
Korean Journal of Anesthesiology
1995 Volume.28 No. 2 p.251 ~ p.254
|
|
|
The Relationships between Onset Time and Recovery of Six Neuromuscular Blocking Drugs
|
|
김성열
이주철/김순임/김선종/박욱
|
|
|
Abstract
|
|
|
There is an evidence that onset time and potency of the non-depolarizing neuromuscular blocking agents are related. However the relationship between onset time and the recovery has not been investigated yet. In this experiment, the onset times of
six
neuromuscular blocking agents have been compared with their recovery times. The neuromuscular transmission of mivacurium 0.15 mg/kg, atracurium 0.4 mg/kg. Vecuronium 0.08 mg/kg pipecuronium 0.08 mg/kg, pancuronium 0.1 mg/kg and succinylcholine 1
mg/kg
were studied in 58 adult healthy patient (ASA I and II) during O20N2O-isoflurane anesthesia using train-of-four stimulation with Relaxograph. It has been demonstrated that there is a close relationship between onset time and recovery in
depolarizing
neuromuscular blocking agent but not in non-depolarizing agents. Consequently, it is proposed that the relationships between the onset time and the recovery may hardly expected in clinical practice following systemic administration of
non-depolarizing
neuromuscular blocking agents.
|
|
|
KEYWORD
|
|
|
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
   
|